PF4V1

The protein encoded by this gene is a chemokine that is highly similar to platelet factor 4. The encoded protein displays a strong antiangiogenic function and is regulated by chemokine (C-X-C motif) receptor 3. This protein also impairs tumor growth and can protect against blood-retinal barrier breakdown in diabetes patients. [provided by RefSeq, Nov 2015]

Description

Platelet factor 4 variant 1

Tissue specificity

Tissue enhanced (intestine, lymphoid tissue)

Predicted location

Secreted to blood

Protein family

Mapped to neXtProt
Mapped to UniProt SWISS-PROT
Plasma proteins
Predicted secreted proteins
Protein evidence (Ezkurdia et al 2014)
Protein evidence (Kim et al 2014)

Chromosome

4 (73853296 - 73854483)

Ensembl ID

ENSG00000109272  (ver. 103.38)

Orthologs

-

UniProt

P10720

neXtProt

NX_P10720

Human splice variants

Protein structure