Explore
Validate
LearnTissue expression
Cell line expression
Protein structure
UCP1
Uncoupling protein 1SLC25A7, UCP
Mitochondrial uncoupling proteins (UCP) are members of the family of mitochondrial anion carrier proteins (MACP). UCPs separate oxidative phosphorylation from ATP synthesis with energy dissipated as heat, also referred to as the mitochondrial proton leak. UCPs facilitate the transfer of anions from the inner to the outer mitochondrial membrane and the return transfer of protons from the outer to the inner mitochondrial membrane. They also reduce the mitochondrial membrane potential in mammalian cells. Tissue specificity occurs for the different UCPs and the exact methods of how UCPs transfer H+/OH- are not known. UCPs contain the three homologous protein domains of MACPs. This gene is expressed only in brown adipose tissue, a specialized tissue which functions to produce heat. [provided by RefSeq, Jul 2008]
Top validated antibodies |
|||||
| Proteintech Group |  23673-1-AP |
36 references | Polyclonal |
WB
EL
IHC
|
|
| R&D Systems | MAB6158 |
8 references | Monoclonal |
WB
ICC
FC
|
|
| Novus Biologicals | MAB6158 |
9 references | Monoclonal |
WB
ICC
FC
|
|
| Invitrogen Antibodies | PA5-29575 |
3 references | Polyclonal |
WB
IHC
OA
|
|
| antibodies-online | ABIN393398 |
5 references | Monoclonal |
WB
EL
|
|
All Antibodies
Filters
Enhanced validation Supportive data in Antibodypedia Data presented on provider website
Data in Antibodypedia (inconclusive)
Recommended by provider