Tissue expression
Cell line expression
Protein structure
ZBTB16
Zinc finger and BTB domain containing 16PLZF, ZNF145
This gene is a member of the Krueppel C2H2-type zinc-finger protein family and encodes a zinc finger transcription factor that contains nine Kruppel-type zinc finger domains at the carboxyl terminus. This protein is located in the nucleus, is involved in cell cycle progression, and interacts with a histone deacetylase. Specific instances of aberrant gene rearrangement at this locus have been associated with acute promyelocytic leukemia (APL). Alternate transcriptional splice variants have been characterized. [provided by RefSeq, Jul 2008]
Top validated antibodies |
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| Invitrogen Antibodies | 2 references | Polyclonal |
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| LSBio | Monoclonal |
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| R&D Systems | 1 references | Monoclonal |
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| Novus Biologicals | 1 references | Monoclonal |
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| NSJ Bioreagents | Polyclonal |
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