Tissue expression
Cell line expression
Protein structure
MTCH2
Mitochondrial carrier 2SLC25A50
This gene encodes a member of the SLC25 family of nuclear-encoded transporters that are localized in the inner mitochondrial membrane. Members of this superfamily are involved in many metabolic pathways and cell functions. Genome-wide association studies in human have identified single-nucleotide polymorphisms in several loci associated with obesity. This gene is one such locus, which is highly expressed in white adipose tissue and adipocytes, and thought to play a regulatory role in adipocyte differentiation and biology. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. A recent study showed this gene to be an authentic stop codon readthrough target that can produce two isoforms from the same mRNA by use of alternative in-frame translation termination codons. [provided by RefSeq, Dec 2017]
Top validated antibodies |
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Proteintech Group | 16888-1-AP | 7 references | Polyclonal |
WB
EL
ICC
IP
IHC
|
|
Invitrogen Antibodies | 16888-1-AP | Polyclonal |
WB
ICC
IP
IHC
OA
|
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NovoPro Bioscience Inc. | 112766 | Polyclonal |
WB
EL
ICC
IP
IHC
|
||
FineTest Biotech | FNab05392 | Polyclonal |
WB
EL
ICC
IP
IHC
|
||
GeneTex | GTX31786 | Polyclonal |
WB
EL
ICC
IHC |
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Supportive data in Antibodypedia
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