Tissue expression
Cell line expression
Protein structure
LDHB
Lactate dehydrogenase BThis gene encodes the B subunit of lactate dehydrogenase enzyme, which catalyzes the interconversion of pyruvate and lactate with concomitant interconversion of NADH and NAD+ in a post-glycolysis process. Alternatively spliced transcript variants have been found for this gene. Recent studies have shown that a C-terminally extended isoform is produced by use of an alternative in-frame translation termination codon via a stop codon readthrough mechanism, and that this isoform is localized in the peroxisomes. Mutations in this gene are associated with lactate dehydrogenase B deficiency. Pseudogenes have been identified on chromosomes X, 5 and 13. [provided by RefSeq, Feb 2016]
Top validated antibodies |
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Proteintech Group | ![]() |
53 references | Polyclonal |
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Invitrogen Antibodies | ![]() |
Polyclonal |
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Novus Biologicals | ![]() |
4 references | Monoclonal |
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Abnova Corporation | ![]() |
3 references | Monoclonal |
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NovoPro Bioscience Inc. | ![]() |
Polyclonal |
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