Tissue expression
Cell line expression
Protein structure
ST8SIA1
ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 1SIAT8, SIAT8A
Gangliosides are membrane-bound glycosphingolipids containing sialic acid. Ganglioside GD3 is known to be important for cell adhesion and growth of cultured malignant cells. The protein encoded by this gene is a type II membrane protein that catalyzes the transfer of sialic acid from CMP-sialic acid to GM3 to produce gangliosides GD3 and GT3. The encoded protein may be found in the Golgi apparatus and is a member of glycosyltransferase family 29. Alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Jan 2015]
Top validated antibodies |
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| Proteintech Group | 7 references | Polyclonal |
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| Novus Biologicals | 1 references | Polyclonal |
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| R&D Systems | 1 references | Polyclonal |
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| Invitrogen Antibodies | Polyclonal |
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| antibodies-online | Polyclonal |
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