Tissue expression
Cell line expression
Protein structure
SRF
Serum response factorMCM1
This gene encodes a ubiquitous nuclear protein that stimulates both cell proliferation and differentiation. It is a member of the MADS (MCM1, Agamous, Deficiens, and SRF) box superfamily of transcription factors. This protein binds to the serum response element (SRE) in the promoter region of target genes. This protein regulates the activity of many immediate-early genes, for example c-fos, and thereby participates in cell cycle regulation, apoptosis, cell growth, and cell differentiation. This gene is the downstream target of many pathways; for example, the mitogen-activated protein kinase pathway (MAPK) that acts through the ternary complex factors (TCFs). Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, May 2014]
Top validated antibodies |
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NSJ Bioreagents | V9737 | Monoclonal |
WB
EL
ICC
IHC
FC
PA
OA
|
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Proteintech Group | 16821-1-AP | 6 references | Polyclonal |
WB
EL
ICC
IP
IHC
|
|
Invitrogen Antibodies | 720240 | 1 references | Polyclonal |
WB
ICC
FC
OA |
|
antibodies-online | ABIN393372 | 5 references | Monoclonal |
WB
EL
IHC
|
|
Boster Biological Technology | A00557-1 | Polyclonal |
WB
EL
ICC
IHC
FC
|
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Supportive data in Antibodypedia
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Recommended by provider