Tissue expression
Cell line expression
Protein structure
COX7A2
Cytochrome c oxidase subunit 7A2COX7AL, COXVIIa-L
Cytochrome c oxidase, the terminal component of the mitochondrial respiratory chain, catalyzes the electron transfer from reduced cytochrome c to oxygen. This component is a heteromeric complex consisting of three catalytic subunits encoded by mitochondrial genes, and multiple structural subunits encoded by nuclear genes. The mitochondrially-encoded subunits function in electron transfer, while the nuclear-encoded subunits may function in the regulation and assembly of the complex. This nuclear gene encodes polypeptide 2 (liver isoform) of subunit VIIa, with this polypeptide being present in both muscle and non-muscle tissues. In addition to polypeptide 2, subunit VIIa includes polypeptide 1 (muscle isoform), which is present only in muscle tissues, and a related protein, which is present in all tissues. Alternative splicing results in multiple transcript variants. Related pseudogenes have been identified on chromosomes 4 and 14. [provided by RefSeq, Oct 2009]
Top validated antibodies |
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LSBio | LS-B6585 | Polyclonal |
WB
EL
IHC
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Proteintech Group | 18122-1-AP | 3 references | Polyclonal |
EL
ICC |
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Invitrogen Antibodies | PA5-99611 | Polyclonal |
WB
ICC
IHC
|
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NovoPro Bioscience Inc. | 109498 | Polyclonal |
WB
EL
ICC
|
||
antibodies-online | ABIN1106825 | Polyclonal |
WB
EL
IHC
|
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