PCDHB6

This gene is a member of the protocadherin beta gene cluster, one of three related gene clusters tandemly linked on chromosome five. The gene clusters demonstrate an unusual genomic organization similar to that of B-cell and T-cell receptor gene clusters. Unlike the alpha and gamma clusters, the transcripts from these genes do not share common 3' exons. These neural cadherin-like cell adhesion proteins are integral plasma membrane proteins that most likely play a critical role in the establishment and function of specific cell-cell neural connections. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Dec 2014]

Description

Protocadherin beta 6

Tissue specificity

Low tissue specificity

Subcell location

Nucleoplasm

Predicted location

Membrane

Protein family

Mapped to neXtProt
Mapped to UniProt SWISS-PROT
Predicted membrane proteins

Chromosome

5 (141150057 - 141153287)

Ensembl ID

ENSG00000113211  (ver. 103.38)

Orthologs

Mouse Pcdhb13: ENSMUSG00000047307

UniProt

Q9Y5E3

neXtProt

NX_Q9Y5E3

Human splice variants
Mouse splice variants

Protein structure