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IL5
Interleukin 5EDF, IL-5, TRF
This gene encodes a cytokine that acts as a growth and differentiation factor for both B cells and eosinophils. The encoded cytokine plays a major role in the regulation of eosinophil formation, maturation, recruitment and survival. The increased production of this cytokine may be related to pathogenesis of eosinophil-dependent inflammatory diseases. This cytokine functions by binding to its receptor, which is a heterodimer, whose beta subunit is shared with the receptors for interleukine 3 (IL3) and colony stimulating factor 2 (CSF2/GM-CSF). This gene is located on chromosome 5 within a cytokine gene cluster which includes interleukin 4 (IL4), interleukin 13 (IL13), and CSF2 . This gene, IL4, and IL13 may be regulated coordinately by long-range regulatory elements spread over 120 kilobases on chromosome 5q31. [provided by RefSeq, Jul 2013]
Top validated antibodies |
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| Invitrogen Antibodies |  14-7052-81 |
17 references | Monoclonal |
EL
IHC
FC
BN
OA
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| GeneTex | GTX39938 |
1 references | Polyclonal |
WB
EL
IHC
FC
FA
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| R&D Systems | MAB405-100 |
11 references | Monoclonal |
EL
FC
BN
|
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| LSBio | LS-C352360 |
Polyclonal |
WB
IP
IHC
|
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| Novus Biologicals | MAB605 |
4 references | Monoclonal |
WB
ICC
FC
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