REG1A

This gene is a type I subclass member of the Reg gene family. The Reg gene family is a multigene family grouped into four subclasses, types I, II, III and IV, based on the primary structures of the encoded proteins. This gene encodes a protein that is secreted by the exocrine pancreas. It is associated with islet cell regeneration and diabetogenesis and may be involved in pancreatic lithogenesis. Reg family members REG1B, REGL, PAP and this gene are tandemly clustered on chromosome 2p12 and may have arisen from the same ancestral gene by gene duplication. [provided by RefSeq, Jul 2008]

Description

Regenerating family member 1 alpha

Tissue specificity

Tissue enriched (pancreas)

Predicted location

Secreted to digestive system

Protein family

Mapped to neXtProt
Mapped to UniProt SWISS-PROT
Plasma proteins
Predicted secreted proteins
Protein evidence (Ezkurdia et al 2014)
Protein evidence (Kim et al 2014)

Chromosome

2 (79120362 - 79123409)

Ensembl ID

ENSG00000115386  (ver. 103.38)

Orthologs

-

UniProt

P05451

neXtProt

NX_P05451

Human splice variants

Protein structure