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FANCL
FA complementation group LFAAP43, FLJ10335, PHF9, Pog
This gene encodes a ubiquitin ligase that is a member of the Fanconi anemia complementation group (FANC). Members of this group are related by their assembly into a common nuclear protein complex rather than by sequence similarity. This gene encodes the protein for complementation group L that mediates monoubiquitination of FANCD2 as well as FANCI. Fanconi anemia is a genetically heterogeneous recessive disorder characterized by cytogenetic instability, hypersensitivity to DNA crosslinking agents, increased chromosomal breakage, and defective DNA repair. Alternative splicing results in multiple transcript variants. [provided by RefSeq, May 2018]
Top validated antibodies |
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| LSBio |  LS-C409045 |
Polyclonal |
WB
IHC
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| Invitrogen Antibodies | PA5-57768 |
1 references | Polyclonal |
WB
ICC
IHC
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| Novus Biologicals | NBP1-84758 |
1 references | Polyclonal |
WB
ICC
IHC
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| Abnova Corporation | H00055120-D01 |
Polyclonal |
WB
ICC
IP
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| Proteintech Group | 14454-1-AP |
Polyclonal |
WB
EL
IHC
|
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