Tissue expression
Cell line expression
Protein structure
MLPH
Melanophilinexophilin-3, l(1)-3Rk, l1Rk3, ln, Slac-2a
This gene encodes a member of the exophilin subfamily of Rab effector proteins. The protein forms a ternary complex with the small Ras-related GTPase Rab27A in its GTP-bound form and the motor protein myosin Va. A similar protein complex in mouse functions to tether pigment-producing organelles called melanosomes to the actin cytoskeleton in melanocytes, and is required for visible pigmentation in the hair and skin. A mutation in this gene results in Griscelli syndrome type 3, which is characterized by a silver-gray hair color and abnormal pigment distribution in the hair shaft. Several alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2013]
Top validated antibodies |
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Proteintech Group | 10338-1-AP | 11 references | Polyclonal |
WB
EL
ICC
IP
IHC
|
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Invitrogen Antibodies | 10338-1-AP | Polyclonal |
WB
ICC
IP
IHC
OA
|
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NovoPro Bioscience Inc. | 112651 | Polyclonal |
WB
EL
ICC
IP
IHC
|
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FineTest Biotech | FNab05120 | Polyclonal |
WB
EL
ICC
IP
IHC
|
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Novus Biologicals | NB300-943 | 2 references | Polyclonal |
WB
EL
ICC
|
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