Tissue expression
Cell line expression
Protein structure
KLF7
Kruppel like factor 7UKLF
The protein encoded by this gene is a member of the Kruppel-like transcriptional regulator family. Members in this family regulate cell proliferation, differentiation and survival and contain three C2H2 zinc fingers at the C-terminus that mediate binding to GC-rich sites. This protein may contribute to the progression of type 2 diabetes by inhibiting insulin expression and secretion in pancreatic beta-cells and by deregulating adipocytokine secretion in adipocytes. A pseudogene of this gene is located on the long arm of chromosome 3. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Aug 2012]
Top validated antibodies |
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| LSBio | Monoclonal |
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| Invitrogen Antibodies | 1 references | Polyclonal |
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| Proteintech Group | 3 references | Polyclonal |
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| antibodies-online | 1 references | Monoclonal |
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| Abnova Corporation | 1 references | Monoclonal |
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