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BCL11A
BAF chromatin remodeling complex subunit BCL11ABCL11A-L, BCL11A-S, BCL11A-XL, CTIP1, EVI9, HBFQTL5, ZNF856
This gene encodes a C2H2 type zinc-finger protein by its similarity to the mouse Bcl11a/Evi9 protein. The corresponding mouse gene is a common site of retroviral integration in myeloid leukemia, and may function as a leukemia disease gene, in part, through its interaction with BCL6. During hematopoietic cell differentiation, this gene is down-regulated. It is possibly involved in lymphoma pathogenesis since translocations associated with B-cell malignancies also deregulates its expression. Multiple transcript variants encoding several different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]
Top validated antibodies |
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| antibodies-online |  ABIN395972 |
5 references | Monoclonal |
WB
EL
ICC
IHC
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| Novus Biologicals | NB600-261 |
6 references | Polyclonal |
WB
IP
FC
ChIP
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| Abnova Corporation | H00053335-M03 |
Monoclonal |
WB
EL
ICC
IHC
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| Invitrogen Antibodies | 53335-MSM1-P0 |
Monoclonal |
WB
EL
ICC
IP
FC
OA
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| Biorbyt | orb1410055 |
Monoclonal |
WB
EL
ICC
IP
FC
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