Tissue expression
Cell line expression
Protein structure
ETF1
Eukaryotic translation termination factor 1ERF, ERF1, RF1, SUP45L1, TB3-1
This gene encodes a class-1 polypeptide chain release factor. The encoded protein plays an essential role in directing termination of mRNA translation from the termination codons UAA, UAG and UGA. This protein is a component of the SURF complex which promotes degradation of prematurely terminated mRNAs via the mechanism of nonsense-mediated mRNA decay (NMD). Alternate splicing results in multiple transcript variants. Pseudogenes of this gene are found on chromosomes 6, 7, and X. [provided by RefSeq, Aug 2013]
Top validated antibodies |
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| Proteintech Group | 1 references | Polyclonal |
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| GeneTex | 2 references | Polyclonal |
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| Novus Biologicals | 2 references | Polyclonal |
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| NSJ Bioreagents | Monoclonal |
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| antibodies-online | 1 references | Polyclonal |
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