Tissue expression
Cell line expression
Protein structure
MYOT
MyotilinLGMD1, LGMD1A, TTID
This gene encodes a cystoskeletal protein which plays a significant role in the stability of thin filaments during muscle contraction. This protein binds F-actin, crosslinks actin filaments, and prevents latrunculin A-induced filament disassembly. Mutations in this gene have been associated with limb-girdle muscular dystrophy and myofibrillar myopathies. Several alternatively spliced transcript variants of this gene have been described, but the full-length nature of some of these variants has not been determined. [provided by RefSeq, Oct 2008]
Top validated antibodies |
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Proteintech Group | ![]() |
8 references | Polyclonal |
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LSBio | ![]() |
Polyclonal |
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Biorbyt | ![]() |
Polyclonal |
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FineTest Biotech | ![]() |
Polyclonal |
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antibodies-online | ![]() |
Polyclonal |
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