Tissue expression
Cell line expression
Protein structure
WWP1
WW domain containing E3 ubiquitin protein ligase 1AIP5, DKFZP434D2111
WW domain-containing proteins are found in all eukaryotes and play an important role in the regulation of a wide variety of cellular functions such as protein degradation, transcription, and RNA splicing. This gene encodes a protein which contains 4 tandem WW domains and a HECT (homologous to the E6-associated protein carboxyl terminus) domain. The encoded protein belongs to a family of NEDD4-like proteins, which are E3 ubiquitin-ligase molecules and regulate key trafficking decisions, including targeting of proteins to proteosomes or lysosomes. Alternative splicing of this gene generates at least 6 transcript variants; however, the full length nature of these transcripts has not been defined. [provided by RefSeq, Jul 2008]
Top validated antibodies |
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Novus Biologicals | H00011059-M01 | 14 references | Monoclonal |
WB
EL
ICC
IP
IHC
|
|
Abnova Corporation | H00011059-M01 | 7 references | Monoclonal |
WB
EL
ICC
IP
IHC
|
|
antibodies-online | ABIN393446 | 5 references | Monoclonal |
WB
EL
ICC
IP
IHC
|
|
Invitrogen Antibodies | H00011059-M01 | Monoclonal |
WB
EL
ICC
IP
IHC
OA |
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Abgent | AT4546a | Monoclonal |
WB
EL
ICC
IP
IHC
|
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Supportive data in Antibodypedia
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Recommended by provider
Supportive data in Antibodypedia
Data presented on provider website
Data in Antibodypedia (inconclusive)
Recommended by provider