Tissue expression
Cell line expression
Protein structure
ACVR1C
Activin A receptor type 1CACVRLK7, ALK7
ACVR1C is a type I receptor for the TGFB (see MIM 190180) family of signaling molecules. Upon ligand binding, type I receptors phosphorylate cytoplasmic SMAD transcription factors, which then translocate to the nucleus and interact directly with DNA or in complex with other transcription factors (Bondestam et al., 2001 [PubMed 12063393]). [supplied by OMIM, Mar 2008]
Top validated antibodies |
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| LSBio | Polyclonal |
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| Proteintech Group | 2 references | Polyclonal |
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| antibodies-online | 4 references | Polyclonal |
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| Invitrogen Antibodies | Polyclonal |
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| Abnova Corporation | 3 references | Polyclonal |
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