TM9SF2

This gene encodes a member of the transmembrane 9 superfamily. The encoded 76 kDa protein localizes to early endosomes in human cells. The encoded protein possesses a conserved and highly hydrophobic C-terminal domain which contains nine transmembrane domains. The protein may play a role in small molecule transport or act as an ion channel. A pseudogene associated with this gene is located on the X chromosome. [provided by RefSeq, Oct 2012]

Description

Transmembrane 9 superfamily member 2

Tissue specificity

Low tissue specificity

Predicted location

Intracellular, Membrane

Protein family

Mapped to neXtProt
Mapped to UniProt SWISS-PROT
Predicted intracellular proteins
Predicted membrane proteins
Protein evidence (Ezkurdia et al 2014)
Protein evidence (Kim et al 2014)
Transporters

Chromosome

13 (99446311 - 99564048)

Ensembl ID

ENSG00000125304  (ver. 103.38)

Orthologs

Mouse Tm9sf2: ENSMUSG00000025544

UniProt

Q99805

neXtProt

NX_Q99805

Human splice variants
Mouse splice variants

Protein structure