CSTL1

The cystatin superfamily encompasses proteins that contain multiple cystatin-like sequences. Some of the members are active cysteine protease inhibitors, while others have lost or perhaps never acquired this inhibitory activity. There are three inhibitory families in the superfamily, including the type 1 cystatins (stefins), type 2 cystatins and the kininogens. The type 2 cystatin proteins are a class of cysteine proteinase inhibitors found in a variety of human fluids and secretions. The cystatin locus on chromosome 20 contains the majority of the type 2 cystatin genes and pseudogenes. This gene is located at the telomeric end of the cystatin locus and encodes a type 2 cystatin-like protein. The specific function of this protein has not been determined. [provided by RefSeq, Jul 2008]

Description

Cystatin like 1

Tissue specificity

Tissue enriched (testis)

Predicted location

Intracellular, Secreted in male reproductive system

Protein family

Mapped to neXtProt
Mapped to UniProt SWISS-PROT
Predicted intracellular proteins
Predicted secreted proteins

Chromosome

20 (23439685 - 23444930)

Ensembl ID

ENSG00000125823  (ver. 103.38)

Orthologs

Mouse Cstl1: ENSMUSG00000055177

UniProt

Q9H114

neXtProt

NX_Q9H114

Human splice variants
Mouse splice variants

Protein structure