Tissue expression
Cell line expression
Protein structure
BCL2L2
BCL2 like 2BCL-W, KIAA0271, PPP1R51
This gene encodes a member of the BCL-2 protein family. The proteins of this family form hetero- or homodimers and act as anti- and pro-apoptotic regulators. Expression of this gene in cells has been shown to contribute to reduced cell apoptosis under cytotoxic conditions. Studies of the related gene in mice indicated a role in the survival of NGF- and BDNF-dependent neurons. Mutation and knockout studies of the mouse gene demonstrated an essential role in adult spermatogenesis. Alternative splicing results in multiple transcript variants. Read-through transcription also exists between this gene and the neighboring downstream PABPN1 (poly(A) binding protein, nuclear 1) gene. [provided by RefSeq, Dec 2010]
Top validated antibodies |
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Invitrogen Antibodies | PA5-78865 | 1 references | Polyclonal |
WB
IHC
FC
OA |
|
antibodies-online | ABIN5682487 | Monoclonal |
WB
EL
ICC
IHC
FC
|
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Novus Biologicals | NBP2-61706 | Monoclonal |
WB
EL
ICC
IHC
FC
|
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LSBio | LS-C353907 | Polyclonal |
WB
ICC
IHC
|
||
Biorbyt | orb2239857 | Polyclonal |
WB
EL
IP
IHC
FC
|
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