Tissue expression
Cell line expression
Protein structure
C12orf65
Chromosome 12 open reading frame 65FLJ38663, SPG55
This nuclear gene encodes a mitochondrial matrix protein that appears to contribute to peptide chain termination in the mitochondrial translation machinery. Two different 1 bp deletions (resulting in the same premature stop codon)result in decreased mitochondrial translation, decreased levels of oxidative phosphorylation complexes and encepthalomyopathy. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Aug 2010]
Top validated antibodies |
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antibodies-online | ![]() |
Polyclonal |
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Abnova Corporation | ![]() |
1 references | Polyclonal |
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Novus Biologicals | ![]() |
1 references | Polyclonal |
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NovoPro Bioscience Inc. | ![]() |
Polyclonal |
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Proteintech Group | ![]() |
Polyclonal |
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