Tissue expression
Cell line expression
Protein structure
COX4I2
Cytochrome c oxidase subunit 4I2COX4-2, COX4B, COX4L2, COXIV-2, dJ857M17.2
Cytochrome c oxidase (COX), the terminal enzyme of the mitochondrial respiratory chain, catalyzes the electron transfer from reduced cytochrome c to oxygen. It is a heteromeric complex consisting of 3 catalytic subunits encoded by mitochondrial genes and multiple structural subunits encoded by nuclear genes. The mitochondrially-encoded subunits function in electron transfer, and the nuclear-encoded subunits may be involved in the regulation and assembly of the complex. This nuclear gene encodes isoform 2 of subunit IV. Isoform 1 of subunit IV is encoded by a different gene, however, the two genes show a similar structural organization. Subunit IV is the largest nuclear encoded subunit which plays a pivotal role in COX regulation. [provided by RefSeq, Jul 2008]
Top validated antibodies |
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Proteintech Group | 11463-1-AP | 17 references | Polyclonal |
WB
EL
ICC
IP
IHC
|
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Novus Biologicals | H00084701-M01 | 10 references | Monoclonal |
WB
EL
IP
IHC |
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Abnova Corporation | H00084701-M01 | 5 references | Monoclonal |
WB
EL
IP
IHC |
|
Invitrogen Antibodies | 11463-1-AP | Polyclonal |
WB
ICC
IP
IHC
OA
|
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antibodies-online | ABIN566588 | 6 references | Monoclonal |
WB
EL
IP
IHC |
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