PCED1A

The protein encoded by this gene is a member of the GDSL/SGNH superfamily. Members of this family are hydrolytic enzymes with esterase and lipase activity and broad substrate specificity. This protein belongs to the Pmr5-Cas1p-esterase subfamily in that it contains the catalytic triad comprised of serine, aspartate and histidine and lacks two conserved regions (glycine after strand S2 and GxND motif). A pseudogene of this gene has been identified on the long arm of chromosome 2. Alternative splicing results in multiple transcript variants that encode different protein isoforms. [provided by RefSeq, Sep 2012]

Description

PC-esterase domain containing 1A

Tissue specificity

Low tissue specificity

Subcell location

Nucleoplasm, Cytosol

Predicted location

Intracellular

Protein family

Mapped to neXtProt
Mapped to UniProt SWISS-PROT
Predicted intracellular proteins

Chromosome

20 (2835314 - 2841190)

Ensembl ID

ENSG00000132635  (ver. 103.38)

Orthologs

Mouse Pced1a: ENSMUSG00000037773

UniProt

Q9H1Q7

neXtProt

NX_Q9H1Q7

Human splice variants
Mouse splice variants

Protein structure