Explore
Validate
LearnTissue expression
Cell line expression
Protein structure
MUTYH
MutY DNA glycosylaseMYH
This gene encodes a DNA glycosylase involved in oxidative DNA damage repair. The enzyme excises adenine bases from the DNA backbone at sites where adenine is inappropriately paired with guanine, cytosine, or 8-oxo-7,8-dihydroguanine, a major oxidatively damaged DNA lesion. The protein is localized to the nucleus and mitochondria. This gene product is thought to play a role in signaling apoptosis by the introduction of single-strand breaks following oxidative damage. Mutations in this gene result in heritable predisposition to colorectal cancer, termed MUTYH-associated polyposis (MAP). Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Apr 2017]
Top validated antibodies |
|||||
| Novus Biologicals |  H00004595-M01 |
10 references | Monoclonal |
WB
EL
ICC
IP
IHC
BN
|
|
| Proteintech Group | 19650-1-AP |
3 references | Polyclonal |
WB
EL
IP
IHC
|
|
| Atlas Antibodies | HPA008732 |
1 references | Polyclonal |
WB
ICC
IHC
|
|
| LSBio | LS-C354036 |
Polyclonal |
WB
ICC
IHC
|
||
| antibodies-online | ABIN561883 |
7 references | Monoclonal |
WB
EL
IP
|
|
All Antibodies
Filters
Enhanced validation Supportive data in Antibodypedia Data presented on provider website
Data in Antibodypedia (inconclusive)
Recommended by provider