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Protein structure
TRPC4
Transient receptor potential cation channel subfamily C member 4HTRP4, TRP4
This gene encodes a member of the canonical subfamily of transient receptor potential cation channels. The encoded protein forms a non-selective calcium-permeable cation channel that is activated by Gq-coupled receptors and tyrosine kinases, and plays a role in multiple processes including endothelial permeability, vasodilation, neurotransmitter release and cell proliferation. Single nucleotide polymorphisms in this gene may be associated with generalized epilepsy with photosensitivity. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Aug 2011]
Top validated antibodies |
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| Novus Biologicals |  NBP1-20989 |
2 references | Polyclonal |
WB
EL
IHC
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| Proteintech Group | 21349-1-AP |
2 references | Polyclonal |
WB
EL
IHC
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| Invitrogen Antibodies | ACC-018-200UL |
Polyclonal |
WB
IP
IHC
OA
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| GeneTex | GTX54758 |
Polyclonal |
WB
ICC
IP
IHC
|
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| LSBio | LS-B6722 |
Monoclonal |
WB
ICC
IP
IHC
BN
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