Tissue expression
Cell line expression
Protein structure
RFXAP
Regulatory factor X associated proteinMajor histocompatibility (MHC) class II molecules are transmembrane proteins that have a central role in development and control of the immune system. The protein encoded by this gene, along with regulatory factor X-associated ankyrin-containing protein and regulatory factor-5, forms a complex that binds to the X box motif of certain MHC class II gene promoters and activates their transcription. Once bound to the promoter, this complex associates with the non-DNA-binding factor MHC class II transactivator, which controls the cell type specificity and inducibility of MHC class II gene expression. Mutations in this gene have been linked to bare lymphocyte syndrome type II, complementation group D. Transcript variants utilizing different polyA signals have been found for this gene. [provided by RefSeq, Jul 2008]
Top validated antibodies |
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LSBio | LS-C198084 | Monoclonal |
WB
EL |
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Invitrogen Antibodies | MA5-19814 | Monoclonal |
WB
EL
OA
|
||
Proteintech Group | 20188-1-AP | Polyclonal |
WB
EL
ICC
|
||
NovoPro Bioscience Inc. | 114636 | Polyclonal |
WB
EL
ICC
|
||
Biorbyt | orb312913 | Polyclonal |
EL
ICC
IHC
|
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Supportive data in Antibodypedia
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Recommended by provider
Supportive data in Antibodypedia
Data presented on provider website
Data in Antibodypedia (inconclusive)
Recommended by provider