Tissue expression
Cell line expression
Protein structure
BEX2
Brain expressed X-linked 2DJ79P11.1
This gene belongs to the brain expressed X-linked gene family. The encoded protein interacts with the transcription factor LIM domain only 2 in a DNA-binding complex that recognizes the E-box element and promotes transcription. This gene has been found to be a tumor suppressor that is silenced in human glioma. In breast cancer cells, this gene product modulates apoptosis in response to estrogen and tamoxifen, and enhances the anti-proliferative effect of tamoxifen. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Dec 2009]
Top validated antibodies |
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| Proteintech Group | 5 references | Polyclonal |
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| NovoPro Bioscience Inc. | Polyclonal |
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| Cusabio Biotech Co., Ltd | Polyclonal |
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| FineTest Biotech | Polyclonal |
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| LSBio | Polyclonal |
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