Tissue expression
Cell line expression
Protein structure
NUMB
NUMB endocytic adaptor proteinC14orf41
The protein encoded by this gene plays a role in the determination of cell fates during development. The encoded protein, whose degradation is induced in a proteasome-dependent manner by MDM2, is a membrane-bound protein that has been shown to associate with EPS15, LNX1, and NOTCH1. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Feb 2016]
Top validated antibodies |
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| Proteintech Group | 6 references | Polyclonal |
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| NSJ Bioreagents | Polyclonal |
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| Everest Biotech | Polyclonal |
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| LSBio | Monoclonal |
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| NovoPro Bioscience Inc. | Polyclonal |
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