Tissue expression
Cell line expression
Protein structure
TRPM1
Transient receptor potential cation channel subfamily M member 1CSNB1C, LTRPC1, MLSN1
This gene encodes a member of the transient receptor potential melastatin subfamily of transient receptor potential ion channels. The encoded protein is a calcium permeable cation channel that is expressed in melanocytes and may play a role in melanin synthesis. Specific mutations in this gene are the cause autosomal recessive complete congenital stationary night blindness-1C. The expression of this protein is inversely correlated with melanoma aggressiveness and as such it is used as a prognostic marker for melanoma metastasis. Alternate splicing results in multiple transcript variants. [provided by RefSeq, Oct 2011]
Top validated antibodies |
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| Proteintech Group | Polyclonal |
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| Invitrogen Antibodies | Polyclonal |
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| Atlas Antibodies | 2 references | Polyclonal |
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| antibodies-online | 2 references | Polyclonal |
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| NovoPro Bioscience Inc. | Polyclonal |
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