NAV1

This gene belongs to the neuron navigator family and is expressed predominantly in the nervous system. The encoded protein contains coiled-coil domains and a conserved AAA domain characteristic for ATPases associated with a variety of cellular activities. This gene is similar to unc-53, a Caenorhabditis elegans gene involved in axon guidance. The exact function of this gene is not known, but it is thought to play a role in in neuronal development and regeneration. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Nov 2009]

Description

Neuron navigator 1

Tissue specificity

Low tissue specificity

Subcell location

Microtubules

Predicted location

Intracellular

Protein family

Mapped to neXtProt
Mapped to UniProt SWISS-PROT
Predicted intracellular proteins
Protein evidence (Ezkurdia et al 2014)
Protein evidence (Kim et al 2014)

Chromosome

1 (201622885 - 201826969)

Ensembl ID

ENSG00000134369  (ver. 103.38)

Orthologs

Mouse Nav1: ENSMUSG00000009418

UniProt

Q8NEY1

neXtProt

NX_Q8NEY1

Human splice variants
Mouse splice variants

Protein structure