Tissue expression
Cell line expression
Protein structure
CDC73
Cell division cycle 73C1orf28, FIHP, HRPT1, HRPT2, parafibromin
This gene encodes a tumor suppressor that is involved in transcriptional and post-transcriptional control pathways. The protein is a component of the the PAF protein complex, which associates with the RNA polymerase II subunit POLR2A and with a histone methyltransferase complex. This protein appears to facilitate the association of 3' mRNA processing factors with actively-transcribed chromatin. Mutations in this gene have been linked to hyperparathyroidism-jaw tumor syndrome, familial isolated hyperparathyroidism, and parathyroid carcinoma. [provided by RefSeq, Jul 2009]
Top validated antibodies |
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Proteintech Group | ![]() |
1 references | Polyclonal |
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Invitrogen Antibodies | ![]() |
2 references | Polyclonal |
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antibodies-online | ![]() |
1 references | Polyclonal |
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NovoPro Bioscience Inc. | ![]() |
Polyclonal |
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FineTest Biotech | ![]() |
Polyclonal |
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