Tissue expression
Cell line expression
Protein structure
DSG3
Desmoglein 3CDHF6
This gene encodes a member of the desmoglein family and cadherin cell adhesion molecule superfamily of proteins. Desmogleins are calcium-binding transmembrane glycoprotein components of desmosomes, cell-cell junctions between epithelial, myocardial, and other cell types. The encoded preproprotein is proteolytically processed to generate the mature glycoprotein. This gene is present in a gene cluster with other desmoglein gene family members on chromosome 18. The encoded protein has been identified as the autoantigen of the autoimmune blistering disease pemphigus vulgaris. [provided by RefSeq, Jan 2016]
Top validated antibodies |
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| Invitrogen Antibodies | 17 references | Monoclonal |
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| Novus Biologicals | 6 references | Monoclonal |
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| antibodies-online | 6 references | Monoclonal |
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| NSJ Bioreagents | Monoclonal |
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| Abnova Corporation | Monoclonal |
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