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Protein structure
CD63
CD63 moleculeME491, MLA1, TSPAN30
The protein encoded by this gene is a member of the transmembrane 4 superfamily, also known as the tetraspanin family. Most of these members are cell-surface proteins that are characterized by the presence of four hydrophobic domains. The proteins mediate signal transduction events that play a role in the regulation of cell development, activation, growth and motility. The encoded protein is a cell surface glycoprotein that is known to complex with integrins. It may function as a blood platelet activation marker. Deficiency of this protein is associated with Hermansky-Pudlak syndrome. Also this gene has been associated with tumor progression. Alternative splicing results in multiple transcript variants encoding different protein isoforms. [provided by RefSeq, Apr 2012]
Top validated antibodies |
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| Novus Biologicals |  NBP2-42225 |
16 references | Monoclonal |
WB
EL
ICC
IP
IHC
FC
IEM
FA
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| Invitrogen Antibodies | MA1-19281 |
6 references | Monoclonal |
ICC
IP
IHC
FC
OA
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| Proteintech Group | 25682-1-AP |
344 references | Polyclonal |
WB
EL
ICC
IHC
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| NSJ Bioreagents | V2070 |
6 references | Monoclonal |
WB
ICC
IHC
FC
|
|
| GeneTex | GTX28219 |
1 references | Monoclonal |
WB
ICC
IP
IHC
FC
|
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