Explore
Validate
LearnTissue expression
Cell line expression
Protein structure
NKX2-1
NK2 homeobox 1BCH, NKX2A, TITF1, TTF-1, TTF1
This gene encodes a protein initially identified as a thyroid-specific transcription factor. The encoded protein binds to the thyroglobulin promoter and regulates the expression of thyroid-specific genes but has also been shown to regulate the expression of genes involved in morphogenesis. Mutations and deletions in this gene are associated with benign hereditary chorea, choreoathetosis, congenital hypothyroidism, and neonatal respiratory distress, and may be associated with thyroid cancer. Multiple transcript variants encoding different isoforms have been found for this gene. This gene shares the symbol/alias 'TTF1' with another gene, transcription termination factor 1, which plays a role in ribosomal gene transcription. [provided by RefSeq, Feb 2014]
Top validated antibodies |
|||||
| Novus Biologicals |  NBP2-34544-0.1 mg |
Monoclonal |
WB
EL
ICC
IP
IHC
FC
|
||
| antibodies-online | ABIN728713 |
2 references | Polyclonal |
WB
ICC
IHC
FC
|
|
| Proteintech Group | 66034-1-Ig |
3 references | Monoclonal |
WB
EL
IHC
|
|
| OriGene | AM50175PU-S |
Monoclonal |
WB
ICC
IP
IHC
FC
|
||
| LSBio | LS-C153753 |
Polyclonal |
WB
EL
ICC
IHC
|
||
All Antibodies
Filters
Enhanced validation Supportive data in Antibodypedia Data presented on provider website
Data in Antibodypedia (inconclusive) Recommended by provider