KIF13A

This gene encodes a member of the kinesin family of microtubule-based motor proteins that function in the positioning of endosomes. This family member can direct mannose-6-phosphate receptor-containing vesicles from the trans-Golgi network to the plasma membrane, and it is necessary for the steady-state distribution of late endosomes/lysosomes. It is also required for the translocation of FYVE-CENT and TTC19 from the centrosome to the midbody during cytokinesis, and it plays a role in melanosome maturation. Alternative splicing of this gene results in multiple transcript variants. [provided by RefSeq, Aug 2011]

Description

Kinesin family member 13A

Tissue specificity

Tissue enhanced (skeletal muscle)

Predicted location

Intracellular

Protein family

Mapped to neXtProt
Mapped to UniProt SWISS-PROT
Predicted intracellular proteins
Protein evidence (Ezkurdia et al 2014)
Protein evidence (Kim et al 2014)

Chromosome

6 (17759183 - 17987635)

Ensembl ID

ENSG00000137177  (ver. 103.38)

Orthologs

Mouse Kif13a: ENSMUSG00000021375

UniProt

Q9H1H9

neXtProt

NX_Q9H1H9

Human splice variants
Mouse splice variants

Protein structure