Explore
Validate
LearnTissue expression
Cell line expression
Protein structure
PIM1
Pim-1 proto-oncogene, serine/threonine kinasePIM
The protein encoded by this gene belongs to the Ser/Thr protein kinase family, and PIM subfamily. This gene is expressed primarily in B-lymphoid and myeloid cell lines, and is overexpressed in hematopoietic malignancies and in prostate cancer. It plays a role in signal transduction in blood cells, contributing to both cell proliferation and survival, and thus provides a selective advantage in tumorigenesis. Both the human and orthologous mouse genes have been reported to encode two isoforms (with preferential cellular localization) resulting from the use of alternative in-frame translation initiation codons, the upstream non-AUG (CUG) and downstream AUG codons (PMIDs:16186805, 1825810). [provided by RefSeq, Aug 2011]
Top validated antibodies |
|||||
| Invitrogen Antibodies |  710504 |
1 references | Polyclonal |
WB
ICC
IHC
OA
|
|
| antibodies-online | ABIN2842038 |
5 references | Polyclonal |
WB
IHC
|
|
| Abgent | AP7932a |
4 references | Polyclonal |
WB
IHC
|
|
| Abnova Corporation | PAB2304 |
3 references | Polyclonal |
WB
IHC
|
|
| Novus Biologicals | H00005292-M05 |
Monoclonal |
WB
EL
ICC
IHC
|
||
All Antibodies
Filters
Enhanced validation Supportive data in Antibodypedia Data presented on provider website
Data in Antibodypedia (inconclusive)
Recommended by provider