CAPN11

Calpains constitute a family of intracellular calcium-dependent cysteine proteases. There are eight members in this superfamily. They consist of a variable 80 kDa subunit and an invariant 30 kDa subunit. This calpain protein appears to have protease activity and calcium-binding ability. A similar mouse protein may play a functional role in spermatogenesis and in the regulation of calcium-dependent signal transduction events during meiosis. [provided by RefSeq, Dec 2008]

Description

Calpain 11

Tissue specificity

Tissue enriched (testis)

Predicted location

Intracellular

Protein family

Enzymes
Mapped to neXtProt
Mapped to UniProt SWISS-PROT
Predicted intracellular proteins
Protein evidence (Kim et al 2014)

Chromosome

6 (44158811 - 44184401)

Ensembl ID

ENSG00000137225  (ver. 103.38)

Orthologs

Mouse Capn11: ENSMUSG00000058626

UniProt

Q9UMQ6

neXtProt

NX_Q9UMQ6

Human splice variants
Mouse splice variants

Protein structure