Tissue expression
Cell line expression
Protein structure
PPP2R1B
Protein phosphatase 2 scaffold subunit AbetaPP2A-Abeta, PR65B
This gene encodes a constant regulatory subunit of protein phosphatase 2. Protein phosphatase 2 is one of the four major Ser/Thr phosphatases, and it is implicated in the negative control of cell growth and division. It consists of a common heteromeric core enzyme, which is composed of a catalytic subunit and a constant regulatory subunit, that associates with a variety of regulatory subunits. The constant regulatory subunit A serves as a scaffolding molecule to coordinate the assembly of the catalytic subunit and a variable regulatory B subunit. This gene encodes a beta isoform of the constant regulatory subunit A. Mutations in this gene have been associated with some lung and colon cancers. Alternatively spliced transcript variants have been described. [provided by RefSeq, Apr 2010]
Top validated antibodies |
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NSJ Bioreagents | F54528 | Monoclonal |
WB
ICC
IHC
FC |
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NovoPro Bioscience Inc. | 121449 | Monoclonal |
WB
EL
ICC
IHC
FC
|
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Proteintech Group | 12621-1-AP | 3 references | Polyclonal |
WB
EL
IHC
|
|
LSBio | LS-B6593 | Polyclonal |
WB
EL
IHC
|
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Boster Biological Technology | A05756-3 | Polyclonal |
WB
EL
IHC
FC |
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