Tissue expression
Cell line expression
Protein structure
SELENOI
Selenoprotein IEPT1, KIAA1724, SELI, SEPI
The multi-pass transmembrane protein encoded by this gene belongs to the CDP-alcohol phosphatidyltransferase class-I family. It catalyzes the transfer of phosphoethanolamine from CDP-ethanolamine to diacylglycerol to produce phosphatidylethanolamine, which is involved in the formation and maintenance of vesicular membranes, regulation of lipid metabolism, and protein folding. This protein is a selenoprotein, containing the rare selenocysteine (Sec) amino acid at its active site. Sec is encoded by the UGA codon, which normally signals translation termination. The 3' UTRs of selenoprotein mRNAs contain a conserved stem-loop structure, designated the Sec insertion sequence (SECIS) element, that is necessary for the recognition of UGA as a Sec codon rather than as a stop signal. Alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Jul 2016]
Top validated antibodies |
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Novus Biologicals | H00085465-A01 | 1 references | Polyclonal |
WB
EL |
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antibodies-online | ABIN566628 | 1 references | Polyclonal |
WB
EL |
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Abnova Corporation | H00085465-A01 | 1 references | Polyclonal |
WB
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LSBio | LS-C170212 | Polyclonal |
WB
|
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Invitrogen Antibodies | PA5-69677 | Polyclonal |
WB
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Supportive data in Antibodypedia
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