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Protein structure
ABCG5
ATP binding cassette subfamily G member 5STSL
The protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This protein is a member of the White subfamily. The protein encoded by this gene functions as a half-transporter to limit intestinal absorption and promote biliary excretion of sterols. It is expressed in a tissue-specific manner in the liver, colon, and intestine. This gene is tandemly arrayed on chromosome 2, in a head-to-head orientation with family member ABCG8. Mutations in this gene may contribute to sterol accumulation and atheroschlerosis, and have been observed in patients with sitosterolemia. [provided by RefSeq, Jul 2008]
Top validated antibodies |
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| antibodies-online |  ABIN1724857 |
2 references | Monoclonal |
WB
EL
IHC
FC
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| Novus Biologicals | NBP2-23488 |
Monoclonal |
WB
EL
ICC
IHC
FC
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| Proteintech Group | 27722-1-AP |
28 references | Polyclonal |
WB
EL
IHC
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| LSBio | LS-C359351 |
Monoclonal |
WB
EL
IHC
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| GeneTex | GTX60788 |
Monoclonal |
WB
EL
IHC
FC
|
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