Tissue expression
Cell line expression
Protein structure
APH1B
Aph-1 homolog B, gamma-secretase subunitAPH-1B, DKFZp564D0372, PSFL
This gene encodes a multi-pass transmembrane protein that is a functional component of the gamma-secretase complex, which also contains presenilin and nicastrin. This protein represents a stabilizing cofactor for the presenilin holoprotein in the complex. The gamma-secretase complex catalyzes the cleavage of integral proteins such as notch receptors and beta-amyloid precursor protein. [provided by RefSeq, Sep 2011]
Top validated antibodies |
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| Biorbyt | Polyclonal |
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| Novus Biologicals | 1 references | Polyclonal |
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| Antibodies.com | Polyclonal |
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| Invitrogen Antibodies | Polyclonal |
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| Cusabio Biotech Co., Ltd | Polyclonal |
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