Tissue expression
Cell line expression
Protein structure
GALNT6
Polypeptide N-acetylgalactosaminyltransferase 6GalNAc-T6
This gene encodes a member of the UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase (GalNAc-T) family of enzymes. GalNAc-Ts initiate mucin-type O-linked glycosylation in the Golgi apparatus by catalyzing the transfer of GalNAc to serine and threonine residues on target proteins. They are characterized by an N-terminal transmembrane domain, a stem region, a lumenal catalytic domain containing a GT1 motif and Gal/GalNAc transferase motif, and a C-terminal ricin/lectin-like domain. GalNAc-Ts have different, but overlapping, substrate specificities and patterns of expression. The encoded protein is capable of glycosylating fibronectin peptide in vitro and is expressed in a fibroblast cell line, indicating that it may be involved in the synthesis of oncofetal fibronectin. [provided by RefSeq, Jul 2008]
Top validated antibodies |
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antibodies-online | ABIN393767 | 5 references | Monoclonal |
WB
EL
IHC
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GeneTex | GTX104602 | 2 references | Polyclonal |
WB
ICC
IHC
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Atlas Antibodies | HPA017086 | Polyclonal |
WB
ICC
IHC
|
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LSBio | LS-C80944 | Polyclonal |
WB
IHC |
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Biorbyt | orb450264 | Polyclonal |
WB
EL
ICC
IHC |
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