Tissue expression
Cell line expression
Protein structure
CYP1A2
Cytochrome P450 family 1 subfamily A member 2CP12, P3-450
This gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. The protein encoded by this gene localizes to the endoplasmic reticulum and its expression is induced by some polycyclic aromatic hydrocarbons (PAHs), some of which are found in cigarette smoke. The enzyme's endogenous substrate is unknown; however, it is able to metabolize some PAHs to carcinogenic intermediates. Other xenobiotic substrates for this enzyme include caffeine, aflatoxin B1, and acetaminophen. The transcript from this gene contains four Alu sequences flanked by direct repeats in the 3' untranslated region. [provided by RefSeq, Jul 2008]
Top validated antibodies |
|||||
Proteintech Group | 19936-1-AP | 19 references | Polyclonal |
WB
EL
ICC
IP
IHC
FC |
|
Invitrogen Antibodies | 19936-1-AP | Polyclonal |
WB
ICC
IP
IHC
FC
OA |
||
antibodies-online | ABIN951775 | 5 references | Polyclonal |
WB
EL
ICC
IHC |
|
NovoPro Bioscience Inc. | 109684 | Polyclonal |
WB
EL
ICC
IP
IHC
FC |
||
GeneTex | GTX84642 | Monoclonal |
WB
ICC
IHC
FC |
All Antibodies
Filters
Enhanced validation
Supportive data in Antibodypedia
Data presented on provider website
Data in Antibodypedia (inconclusive)
Recommended by provider
Supportive data in Antibodypedia
Data presented on provider website
Data in Antibodypedia (inconclusive)
Recommended by provider