Tissue expression
Cell line expression
Protein structure
CDH11
Cadherin 11CAD11, OB
This gene encodes a type II classical cadherin from the cadherin superfamily, integral membrane proteins that mediate calcium-dependent cell-cell adhesion. Mature cadherin proteins are composed of a large N-terminal extracellular domain, a single membrane-spanning domain, and a small, highly conserved C-terminal cytoplasmic domain. Type II (atypical) cadherins are defined based on their lack of a HAV cell adhesion recognition sequence specific to type I cadherins. Expression of this particular cadherin in osteoblastic cell lines, and its upregulation during differentiation, suggests a specific function in bone development and maintenance. [provided by RefSeq, Jul 2008]
Top validated antibodies |
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| Novus Biologicals | 2 references | Monoclonal |
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| Invitrogen Antibodies | 19 references | Polyclonal |
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| LSBio | Polyclonal |
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| antibodies-online | Monoclonal |
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| R&D Systems | 5 references | Polyclonal |
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