Tissue expression
Cell line expression
Protein structure
PADI1
Peptidyl arginine deiminase 1HPAD10, PAD1, PDI, PDI1
This gene encodes a member of the peptidyl arginine deiminase family of enzymes, which catalyze the post-translational deimination of proteins by converting arginine residues into citrullines in the presence of calcium ions. The family members have distinct substrate specificities and tissue-specific expression patterns. The type I enzyme is involved in the late stages of epidermal differentiation, where it deiminates filaggrin and keratin K1, which maintains hydration of the stratum corneum, and hence the cutaneous barrier function. This enzyme may also play a role in hair follicle formation. This gene exists in a cluster with four other paralogous genes. [provided by RefSeq, Jul 2008]
Top validated antibodies |
|||||
antibodies-online | ABIN1108562 | 2 references | Polyclonal |
WB
IHC |
|
Atlas Antibodies | HPA062294 | Polyclonal |
ICC
IHC |
||
OriGene | AP55147PU-N | Polyclonal |
WB
EL
IHC
|
||
Acris Antibodies GmbH | AP55147PU-N | Polyclonal |
WB
EL
IHC
|
||
Invitrogen Antibodies | PA5-119333 | Polyclonal |
WB
IHC |
All Antibodies
Filters
Enhanced validation
Supportive data in Antibodypedia
Data presented on provider website
Data in Antibodypedia (inconclusive)
Recommended by provider
Supportive data in Antibodypedia
Data presented on provider website
Data in Antibodypedia (inconclusive)
Recommended by provider