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Protein structure
NUF2
NUF2 component of NDC80 kinetochore complexCDCA1, CT106, NUF2R
This gene encodes a protein that is highly similar to yeast Nuf2, a component of a conserved protein complex associated with the centromere. Yeast Nuf2 disappears from the centromere during meiotic prophase when centromeres lose their connection to the spindle pole body, and plays a regulatory role in chromosome segregation. The encoded protein is found to be associated with centromeres of mitotic HeLa cells, which suggests that this protein is a functional homolog of yeast Nuf2. Alternatively spliced transcript variants that encode the same protein have been described. [provided by RefSeq, Jul 2008]
Top validated antibodies |
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| Proteintech Group |  15731-1-AP |
5 references | Polyclonal |
WB
EL
IP
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| antibodies-online | ABIN872897 |
1 references | Polyclonal |
WB
EL
ICC
IHC
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| Invitrogen Antibodies | 37-6800 |
1 references | Monoclonal |
WB
EL
ICC
IP
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| LSBio | LS-C820417 |
Polyclonal |
WB
IP
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| Biorbyt | orb2325340 |
Recombinant |
WB
ICC
IHC
FC
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