LHX9

This gene encodes a member of the LIM homeobox gene family of developmentally expressed transcription factors. The encoded protein contains a homeodomain and two cysteine-rich zinc-binding LIM domains involved in protein-protein interactions. The protein is highly similar to a mouse protein that causes gonadal agenesis when inactivated, suggesting a role in gonadal development. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jul 2008]

Description

LIM homeobox 9

Tissue specificity

Tissue enhanced (brain, ovary)

Subcell location

Nucleoplasm

Predicted location

Intracellular

Protein family

Mapped to neXtProt
Mapped to UniProt SWISS-PROT
Predicted intracellular proteins
Transcription factors

Chromosome

1 (197911902 - 197935478)

Ensembl ID

ENSG00000143355  (ver. 103.38)

Orthologs

Mouse Lhx9: ENSMUSG00000019230

UniProt

Q9NQ69

neXtProt

NX_Q9NQ69

Human splice variants
Mouse splice variants

Protein structure