CRNN

This gene encodes a member of the ""fused gene"" family of proteins, which contain N-terminus EF-hand domains and multiple tandem peptide repeats. The encoded protein contains two EF-hand Ca2+ binding domains in its N-terminus and two glutamine- and threonine-rich 60 amino acid repeats in its C-terminus. This gene, also known as squamous epithelial heat shock protein 53, may play a role in the mucosal/epithelial immune response and epidermal differentiation. [provided by RefSeq, Jan 2009]

Description

Cornulin

Tissue specificity

Tissue enhanced (esophagus, vagina)

Predicted location

Intracellular

Protein family

Disease related genes
Mapped to neXtProt
Mapped to UniProt SWISS-PROT
Predicted intracellular proteins
Protein evidence (Ezkurdia et al 2014)
Protein evidence (Kim et al 2014)

Chromosome

1 (152409243 - 152414263)

Ensembl ID

ENSG00000143536  (ver. 103.38)

Orthologs

Mouse Crnn: ENSMUSG00000078657

UniProt

Q9UBG3

neXtProt

NX_Q9UBG3

Human splice variants
Mouse splice variants

Protein structure